Comparative Study of Immune Cells Infiltration in Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma of the Head and Neck

Background: The role of tumor-associated tissue eosinophils and mast cells in the biological behavior tumors remains unclear. Objectives: This study was performed to compare eosinophil cell counts cutaneous squamous carcinoma (cSCC) basal (BCC) head neck evaluate their relationship with clinicopathologic factors. Methods: current descriptive-analytical conducted on histopathologic slides 46 BCC 30 cSCC samples prepared by using Sirius red Toluidine blue staining techniques for counts, respectively. data were analyzed, Pearson’s correlation, t test, ANOVA test. Results: had mean 35.43 ± 35 331.27 321.68 eosinophil/10 HPF, respectively, this difference statistically significant (P = 0.001). levels infiltration obtained as 55.33 39.90 63.67 40.86 cSCC, However, variable not significantly different between two groups 0.380). In addition, higher grade III than other grades; however, only cells. Furthermore, eosinophil/mast count showed no age gender. Conclusions: Considering greater presence BCC, may be concluded among factors responsible more biologically clinically invasive behaviors compared those BCC.